Human twinning is not linked to the region of chromosome 4 syntetic with the sheep twinning gene FecB
The tendency to dizygotic (DZ) twinning is inherited in both humans and sheep, and a fecundity gene in sheep (FecB) maps to sheep chromosome 6, syntenic with human 4q21-25. Our aim was to see whether a gene predisposing to human DZ twinning mapped to this region. DNA was collected from 169 pairs and 17 sets of 3 sisters (trios) from Australia and New Zealand who had each had spontaneous DZ twins, mostly before the age of 35, and from a replication sample of 111 families (92 affected sister pairs) from The Netherlands. Exclusion mapping was carried out after typing 26 markers on chromosome 4, o... Mehr ...
| Verfasser: |
Duffy, DL
Montgomery, GW
Hall, J.
Mayne, C.
Healy, S.C.
Brown, J
Boomsma, D.I.
Martin, N.G. |
| Dokumenttyp: |
Artikel |
| Erscheinungsdatum: |
2001 |
| Reihe/Periodikum: |
Duffy , DL , Montgomery , GW , Hall , J , Mayne , C , Healy , S C , Brown , J , Boomsma , D I & Martin , N G 2001 , ' Human twinning is not linked to the region of chromosome 4 syntetic with the sheep twinning gene FecB ' , American Journal of Medical Genetics , vol. 100 , no. 3 , pp. 182-186 . https://doi.org/10.1002/ajmg.1255 |
| Schlagwörter: |
/dk/atira/pure/keywords/cohort_studies/netherlands_twin_register_ntr_
/ name=Netherlands Twin Register (NTR)
/ /dk/atira/pure/sustainabledevelopmentgoals/reduced_inequalities
/ name=SDG 10 - Reduced Inequalities |
| Sprache: |
Englisch |
| Permalink: |
https://search.fid-benelux.de/Record/base-26844772 |
| Datenquelle: |
BASE;
Originalkatalog |
| Powered By: |
BASE |
| Link(s) :
|
https://research.vu.nl/en/publications/a08c4bf7-63ca-41bd-9ce6-e84d51ce4784 |
