HLA and genome wide allele sharing in dizygotic twins.
Gametic selection during fertilization or the effects of specific genotypes on the viability of embryos may cause a skewed transmission of chromosomes to surviving offspring. A recent analysis of transmission distortion in humans reported significant excess sharing among full siblings. Dizygotic (DZ) twin pairs are a special case of the simultaneous survival of two genotypes, and there have been reports of DZ pairs with excess allele sharing around the HLA locus, a candidate locus for embryo survival. We performed an allele-sharing study of 1,592 DZ twin pairs from two independent Australian c... Mehr ...
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| Dokumenttyp: | Artikel |
| Erscheinungsdatum: | 2006 |
| Reihe/Periodikum: | Montgomery , GW , Zhu , G , Hottenga , J J , Duffy , DL , Heath , A C , Boomsma , D I , Martin , N G & Visscher , P M 2006 , ' HLA and genome wide allele sharing in dizygotic twins. ' , American Journal of Human Genetics , vol. 79 , no. 6 , pp. 1052-1058 . https://doi.org/10.1086/510136 |
| Schlagwörter: | /dk/atira/pure/keywords/cohort_studies/netherlands_twin_register_ntr_ / name=Netherlands Twin Register (NTR) |
| Sprache: | Englisch |
| Permalink: | https://search.fid-benelux.de/Record/base-26844420 |
| Datenquelle: | BASE; Originalkatalog |
| Powered By: | BASE |
| Link(s) : | https://research.vu.nl/en/publications/8d0722ee-257a-4876-bd8f-24eaae811a6f |
