Association of amyloid pathology with memory performance and cognitive complaints in cognitively normal older adults:a monozygotic twin study
Amyloid pathology in cognitively normal older adults has been associated with low memory performance and cognitive complaints, but findings are conflicting. Using a monozygotic twin design, we further explored this relation. We investigated 199 cognitively normal older adults (96 twin pairs) and assessed cognitive performance, cognitive complaints, and amyloid pathology on positron emission tomography and in the cerebrospinal fluid (CSF). Participants were on average 70.5 (SD = 7.6) years and 114 (57%) were female. Amyloid–positron emission tomography abnormality on visual read and lower CSF a... Mehr ...
Verfasser: |
Konijnenberg, Elles
den Braber, Anouk
ten Kate, Mara
Tomassen, Jori
Mulder, Sandra D.
Yaqub, Maqsood
Teunissen, Charlotte E.
Lammertsma, Adriaan A.
van Berckel, Bart N.M.
Scheltens, Philip
Boomsma, Dorret I.
Visser, Pieter Jelle |
Dokumenttyp: |
Artikel |
Erscheinungsdatum: |
2019 |
Reihe/Periodikum: |
Konijnenberg , E , den Braber , A , ten Kate , M , Tomassen , J , Mulder , S D , Yaqub , M , Teunissen , C E , Lammertsma , A A , van Berckel , B N M , Scheltens , P , Boomsma , D I & Visser , P J 2019 , ' Association of amyloid pathology with memory performance and cognitive complaints in cognitively normal older adults : a monozygotic twin study ' , Neurobiology of Aging , vol. 77 , pp. 58-65 . https://doi.org/10.1016/j.neurobiolaging.2019.01.006 |
Schlagwörter: |
Amyloid aggregation
/ Cognitive complaints
/ Memory performance
/ Monozygotic twins
/ /dk/atira/pure/keywords/cohort_studies/netherlands_twin_register_ntr_
/ name=Netherlands Twin Register (NTR) |
Sprache: |
Englisch |
Permalink: |
https://search.fid-benelux.de/Record/base-26844330 |
Datenquelle: |
BASE;
Originalkatalog |
Powered By: |
BASE |
Link(s) :
|
https://research.vu.nl/en/publications/82a6ca60-98aa-4d21-938b-90b21c828973 |