Optical coherence tomography angiography in preclinical Alzheimer's disease
BACKGROUND/AIMS: As a protrusion from the brain, the retina might reflect the status of the brain. Previous studies showed a decrease in vessel density and foveal avascular zone (FAZ) enlargement on optical coherence tomography angiography (OCTA) in individuals suffering from Alzheimer's disease (AD). This study aims to assess whether such changes are already present in preclinical stages of AD, in a population of monozygotic (MZ) twins. METHODS: 124 cognitively healthy individuals (MZ twins, ages 60-93 years) underwent [18F]flutemetamol amyloid positron emission tomography (PET) scanning and... Mehr ...
| Verfasser: |
van de Kreeke, Jacoba Alida
Nguyen, Hoang-Ton
Konijnenberg, Elles
Tomassen, Jori
den Braber, Anouk
Ten Kate, Mara
Yaqub, Maqsood
van Berckel, Bart
Lammertsma, Adriaan A
Boomsma, Dorret I
Tan, Stevie H
Verbraak, Frank
Visser, Pieter Jelle |
| Dokumenttyp: |
Artikel |
| Erscheinungsdatum: |
2020 |
| Reihe/Periodikum: |
van de Kreeke , J A , Nguyen , H-T , Konijnenberg , E , Tomassen , J , den Braber , A , Ten Kate , M , Yaqub , M , van Berckel , B , Lammertsma , A A , Boomsma , D I , Tan , S H , Verbraak , F & Visser , P J 2020 , ' Optical coherence tomography angiography in preclinical Alzheimer's disease ' , British Journal of Ophthalmology , vol. 104 , no. 2 , pp. 157-161 . https://doi.org/10.1136/bjophthalmol-2019-314127 |
| Schlagwörter: |
/dk/atira/pure/keywords/cohort_studies/netherlands_twin_register_ntr_
/ name=Netherlands Twin Register (NTR) |
| Sprache: |
Englisch |
| Permalink: |
https://search.fid-benelux.de/Record/base-26844255 |
| Datenquelle: |
BASE;
Originalkatalog |
| Powered By: |
BASE |
| Link(s) :
|
https://research.vu.nl/en/publications/7aa5e237-829b-4fe1-9be6-71d6863f05fd |
