Background Metabolomics, defined as the comprehensive identification and quantification of low-molecular-weight metabolites to be found in a biological sample, has been put forward as a potential tool for classifying individuals according to their risk of coronary heart disease (CHD). Here, we investigated whether a single-point blood measurement of the metabolome is associated with and predictive for the risk of CHD. Methods and results We obtained proton nuclear magnetic resonance spectra in 79 cases who developed CHD during follow-up (median 8.1 years) and in 565 randomly selected individua... Mehr ...
| Verfasser: |
Vaarhorst, A.A.M.
Verhoeven, A.
Weller, C.M.
Böhringer, S.
Göraler, S.
Meissner, A.
Deelder, A.M.
Henneman, P.
Gorgels, A.P.M.
van den Brandt, P.A.
Schouten, L.J.
van Greevenbroek, M.M.
Merry, A.H.H.
Verschuren, W.M.M.
van den Maagdenberg, A.M.J.M.
Willems van Dijk, K.
Isaacs, A.
Boomsma, D.I.
Oostra, B.A.
van Duijn, C.M.
Jukema, J.W.
Boer, J.M.A.
Feskens, E.
Heijmans, B.T.
Slagboom, P.E. |
| Dokumenttyp: |
Artikel |
| Erscheinungsdatum: |
2014 |
| Reihe/Periodikum: |
Vaarhorst , A A M , Verhoeven , A , Weller , C M , Böhringer , S , Göraler , S , Meissner , A , Deelder , A M , Henneman , P , Gorgels , A P M , van den Brandt , P A , Schouten , L J , van Greevenbroek , M M , Merry , A H H , Verschuren , W M M , van den Maagdenberg , A M J M , Willems van Dijk , K , Isaacs , A , Boomsma , D I , Oostra , B A , van Duijn , C M , Jukema , J W , Boer , J M A , Feskens , E , Heijmans , B T & Slagboom , P E 2014 , ' A metabolomic profile is associated with the risk of incident coronary heart disease ' , American Heart Journal , vol. 168 , no. 1 , pp. 45-52 . https://doi.org/10.1016/j.ahj.2014.01.019 |
| Schlagwörter: |
/dk/atira/pure/keywords/cohort_studies/netherlands_twin_register_ntr_
/ name=Netherlands Twin Register (NTR)
/ /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being
/ name=SDG 3 - Good Health and Well-being |
| Sprache: |
Englisch |
| Permalink: |
https://search.fid-benelux.de/Record/base-26844183 |
| Datenquelle: |
BASE;
Originalkatalog |
| Powered By: |
BASE |
| Link(s) :
|
https://research.vu.nl/en/publications/705e892b-9601-4ea7-b8de-236daf372e87 |
