An increasing number of genome-wide association (GWA) studies are now using the higher resolution 1000 Genomes Project reference panel (1000G) for imputation, with the expectation that 1000G imputation will lead to the discovery of additional associated loci when compared to HapMap imputation. In order to assess the improvement of 1000G over HapMap imputation in identifying associated loci, we compared the results of GWA studies of circulating fibrinogen based on the two reference panels. Using both HapMap and 1000G imputation we performed a meta-analysis of 22 studies comprising the same 91,9... Mehr ...
| Verfasser: |
de Vries, Paul S
Sabater-Lleal, Maria
Chasman, Daniel I
Trompet, Stella
Ahluwalia, Tarunveer S
Teumer, Alexander
Kleber, Marcus E
Chen, Ming-Huei
Wang, Jie Jin
Attia, John R
Marioni, Riccardo E
Steri, Maristella
Weng, Lu-Chen
Pool, Rene
Grossmann, Vera
Brody, Jennifer A
Venturini, Cristina
Tanaka, Toshiko
Rose, Lynda M
Oldmeadow, Christopher
Mazur, Johanna
Basu, Saonli
Frånberg, Mattias
Yang, Qiong
Ligthart, Symen
Hottenga, Jouke J
Rumley, Ann
Mulas, Antonella
De Craen, Anton J M
Grotevendt, Anne
Taylor, Kent D
Delgado, Graciela E
Kifley, Annette
Lopez, Lorna M
Berentzen, Tina L
Mangino, Massimo
Bandinelli, Stefania
Morrison, Alanna C
Hamsten, Anders
Tofler, Geoffrey
de Maat, Moniek P M
Draisma, Harmen H M
Lowe, Gordon D
Zoledziewska, Magdalena
Sattar, Naveed
Lackner, Karl J
Völker, Uwe
McKnight, Barbara
Huang, Jie
Holliday, Elizabeth G
McEvoy, Mark A
Starr, John M
Hysi, Pirro G
Hernandez, Dena G
Guan, Weihua
Rivadeneira, Fernando
McArdle, Wendy L
Slagboom, P. Eline
Zeller, Tanja
Psaty, Bruce M
Uitterlinden, André G
de Geus, Eco J C
Stott, David J
Binder, Harald
Hofman, Albert
Franco, Oscar H
Rotter, Jerome I
Ferrucci, Luigi
Spector, Tim D
Deary, Ian J
März, Winfried
Greinacher, Andreas
Wild, Philipp S
Cucca, Francesco
Boomsma, Dorret I
Watkins, Hugh
Tang, Weihong
Ridker, Paul M
Jukema, Jan W
Scott, Rodney J
Mitchell, Paul
Hansen, Torben
O'Donnell, Christopher J
Smith, Nicholas L
Strachan, David P
Dehghan, Abbas |
| Dokumenttyp: |
Artikel |
| Erscheinungsdatum: |
2017 |
| Reihe/Periodikum: |
de Vries , P S , Sabater-Lleal , M , Chasman , D I , Trompet , S , Ahluwalia , T S , Teumer , A , Kleber , M E , Chen , M-H , Wang , J J , Attia , J R , Marioni , R E , Steri , M , Weng , L-C , Pool , R , Grossmann , V , Brody , J A , Venturini , C , Tanaka , T , Rose , L M , Oldmeadow , C , Mazur , J , Basu , S , Frånberg , M , Yang , Q , Ligthart , S , Hottenga , J J , Rumley , A , Mulas , A , De Craen , A J M , Grotevendt , A , Taylor , K D , Delgado , G E , Kifley , A , Lopez , L M , Berentzen , T L , Mangino , M , Bandinelli , S , Morrison , A C , Hamsten , A , Tofler , G , de Maat , M P M , Draisma , H H M , Lowe , G D , Zoledziewska , M , Sattar , N , Lackner , K J , Völker , U , McKnight , B , Huang , J , Holliday , E G , McEvoy , M A , Starr , J M , Hysi , P G , Hernandez , D G , Guan , W , Rivadeneira , F , McArdle , W L , Slagboom , P E , Zeller , T , Psaty , B M , Uitterlinden , A G , de Geus , E J C , Stott , D J , Binder , H , Hofman , A , Franco , O H , Rotter , J I , Ferrucci , L , Spector , T D , Deary , I J , März , W , Greinacher , A , Wild , P S , Cucca , F , Boomsma , D I , Watkins , H , Tang , W , Ridker , P M , Jukema , J W , Scott , R J , Mitchell , P , Hansen , T , O'Donnell , C J , Smith , N L , Strachan , D P & Dehghan , A 2017 , ' Comparison of HapMap and 1000 Genomes Reference Panels in a Large-Scale Genome-Wide Association Study ' , PLoS ONE , vol. 12 , no. 1 , e0167742 , pp. e0167742 . https://doi.org/10.1371/journal.pone.0167742 |
| Schlagwörter: |
Journal Article
/ /dk/atira/pure/keywords/cohort_studies/netherlands_twin_register_ntr_
/ name=Netherlands Twin Register (NTR) |
| Sprache: |
Englisch |
| Permalink: |
https://search.fid-benelux.de/Record/base-26844003 |
| Datenquelle: |
BASE;
Originalkatalog |
| Powered By: |
BASE |
| Link(s) :
|
https://research.vu.nl/en/publications/5d116b0a-bf29-4078-bcc0-8abd5e043627 |
