Genetic Basis of a Cognitive Complexity Metric

Relational complexity (RC) is a metric reflecting capacity limitation in relational processing. It plays a crucial role in higher cognitive processes and is an endophenotype for several disorders. However, the genetic underpinnings of complex relational processing have not been investigated. Using the classical twin model, we estimated the heritability of RC and genetic overlap with intelligence (IQ), reasoning, and working memory in a twin and sibling sample aged 15-29 years (N = 787). Further, in an exploratory search for genetic loci contributing to RC, we examined associated genetic marker... Mehr ...

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Verfasser: Hansell, N.K.
Halford, G.S.
Andrews, G.
Shum, D.H.K.
Harris, S.E.
Davies, G.
Franic, S.
Christoforou, A.
Zietsch, B.
Painter, J.
Medland, S.E.
Ehli, E.A.
Davies, G.E.
Steen, V.M.
Lundervold, A.J.
Reinvang, I.
Montgomery, G.W.
Espeseth, T.
Hulshoff Pol, H.E.
Starr, J.M.
Martin, N.G.
Le Hellard, S.
Boomsma, D.I.
Deary, I.J.
Wright, M.J.
Dokumenttyp: Artikel
Erscheinungsdatum: 2015
Reihe/Periodikum: Hansell , N K , Halford , G S , Andrews , G , Shum , D H K , Harris , S E , Davies , G , Franic , S , Christoforou , A , Zietsch , B , Painter , J , Medland , S E , Ehli , E A , Davies , G E , Steen , V M , Lundervold , A J , Reinvang , I , Montgomery , G W , Espeseth , T , Hulshoff Pol , H E , Starr , J M , Martin , N G , Le Hellard , S , Boomsma , D I , Deary , I J & Wright , M J 2015 , ' Genetic Basis of a Cognitive Complexity Metric ' , PLoS ONE , vol. 10 , no. 4 , e0123886 , pp. e0123886 . https://doi.org/10.1371/journal.pone.0123886
Schlagwörter: /dk/atira/pure/keywords/cohort_studies/netherlands_twin_register_ntr_ / name=Netherlands Twin Register (NTR)
Sprache: Englisch
Permalink: https://search.fid-benelux.de/Record/base-26843916
Datenquelle: BASE; Originalkatalog
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Link(s) : https://research.vu.nl/en/publications/52a4a239-319e-42c6-8426-d7503391fa41