Several clinical studies suggest the involvement of premature ageing processes in chronic obstructive pulmonary disease (COPD). Using an epidemiological approach, we studied whether accelerated ageing indicated by telomere length, a marker of biological age, is associated with COPD and asthma, and whether intrinsic age-related processes contribute to the interindividual variability of lung function. Our meta-analysis of 14 studies included 934 COPD cases with 15 846 controls defined according to the Global Lungs Initiative (GLI) criteria (or 1189 COPD cases according to the Global Initiative f... Mehr ...
| Verfasser: |
Albrecht, E.
Sillanpää, E.
Karrasch, S.
Alves, A.C.
Codd, V.
Hovatta, I.
Buxton, J.L.
Nelson, C.P.
Broer, L.
Hägg, S.
Mangino, M.
Willemsen, G.
Surakka, I.
Ferreira, M.A.
Amin, N.
Oostra, B.A.
Bäckmand, H.M.
Peltonen, M.
Sarna, T.
Rantanen, T.
Sipilä, S.
Korhonen, T.
Madden, P.A.
Gieger, C.
Jörres, R.A.
Heinrich, J.
Behr, J.
Huber, R.M.
Peters, A.
Strauch, K.
Wichmann, H.E.
Waldenberger, M.
Blakemore, A.I.
de Geus, E.J.C.
Nyholt, DR
Henders, A.K.
Piirilä, P.L.
Rissanen, A
Magnusson, P.K.
Vinuela, A.
Pietilainen, K.H.
Martin, N.G.
Pedersen, N.L.
Boomsma, D.I.
Spector, T.D.
van Duijn, C.M.
Kaprio, J.
Samani, N.J.
Järvelin, M.R.
Schulz, H. |
| Dokumenttyp: |
Artikel |
| Erscheinungsdatum: |
2014 |
| Reihe/Periodikum: |
Albrecht , E , Sillanpää , E , Karrasch , S , Alves , A C , Codd , V , Hovatta , I , Buxton , J L , Nelson , C P , Broer , L , Hägg , S , Mangino , M , Willemsen , G , Surakka , I , Ferreira , M A , Amin , N , Oostra , B A , Bäckmand , H M , Peltonen , M , Sarna , T , Rantanen , T , Sipilä , S , Korhonen , T , Madden , P A , Gieger , C , Jörres , R A , Heinrich , J , Behr , J , Huber , R M , Peters , A , Strauch , K , Wichmann , H E , Waldenberger , M , Blakemore , A I , de Geus , E J C , Nyholt , DR , Henders , A K , Piirilä , P L , Rissanen , A , Magnusson , P K , Vinuela , A , Pietilainen , K H , Martin , N G , Pedersen , N L , Boomsma , D I , Spector , T D , van Duijn , C M , Kaprio , J , Samani , N J , Järvelin , M R & Schulz , H 2014 , ' Telomere Length in Circulating Leukocytes is Associated with Lung Function and Disease ' , European Respiratory Journal , vol. 43 , no. 4 , pp. 983-992 . https://doi.org/10.1183/09031936.00046213 |
| Schlagwörter: |
/dk/atira/pure/keywords/cohort_studies/netherlands_twin_register_ntr_
/ name=Netherlands Twin Register (NTR)
/ /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being
/ name=SDG 3 - Good Health and Well-being |
| Sprache: |
Englisch |
| Permalink: |
https://search.fid-benelux.de/Record/base-26843241 |
| Datenquelle: |
BASE;
Originalkatalog |
| Powered By: |
BASE |
| Link(s) :
|
https://research.vu.nl/en/publications/118b5fb3-4865-4293-8f39-4a23d49e473c |
