BackgroundDepression and obesity are highly prevalent, and major impacts on public health frequently co-occur. Recently, we reported that having depression moderates the effect of the FTO gene, suggesting its implication in the association between depression and obesity. AimsTo confirm these findings by investigating the FTO polymorphism rs9939609 in new cohorts, and subsequently in a meta-analysis. MethodThe sample consists of 6902 individuals with depression and 6799 controls from three replication cohorts and two original discovery cohorts. Linear regression models were performed to test fo... Mehr ...
| Verfasser: |
Rivera, Margarita
Locke, Adam E
Corre, Tanguy
Czamara, Darina
Wolf, Christiane
Ching-Lopez, Ana
Milaneschi, Yuri
Kloiber, Stefan
Cohen-Woods, Sara
Rucker, James
Aitchison, Katherine J
Bergmann, Sven
Boomsma, Dorret I
Craddock, Nick
Gill, Michael
Holsboer, Florian
Hottenga, Jouke-Jan
Korszun, Ania
Kutalik, Zoltan
Lucae, Susanne
Maier, Wolfgang
Mors, Ole
Müller-Myhsok, Bertram
Owen, Michael J
Penninx, Brenda W J H
Preisig, Martin
Rice, John P
Rietschel, Marcella
Tozzi, Federica
Uher, Rudolf
Vollenweider, Peter
Waeber, Gerard
Willemsen, Gonneke
Craig, Ian W
Farmer, Anne E
Lewis, Cathryn M
Breen, Gerome
McGuffin, Peter |
| Dokumenttyp: |
Artikel |
| Erscheinungsdatum: |
2017 |
| Reihe/Periodikum: |
Rivera , M , Locke , A E , Corre , T , Czamara , D , Wolf , C , Ching-Lopez , A , Milaneschi , Y , Kloiber , S , Cohen-Woods , S , Rucker , J , Aitchison , K J , Bergmann , S , Boomsma , D I , Craddock , N , Gill , M , Holsboer , F , Hottenga , J-J , Korszun , A , Kutalik , Z , Lucae , S , Maier , W , Mors , O , Müller-Myhsok , B , Owen , M J , Penninx , B W J H , Preisig , M , Rice , J P , Rietschel , M , Tozzi , F , Uher , R , Vollenweider , P , Waeber , G , Willemsen , G , Craig , I W , Farmer , A E , Lewis , C M , Breen , G & McGuffin , P 2017 , ' Interaction between the FTO gene, body mass index and depression: meta-analysis of 13701 individuals ' , British Journal of Psychiatry , vol. 211 , no. 2 , pp. 70-76 . https://doi.org/10.1192/bjp.bp.116.183475 |
| Schlagwörter: |
Journal Article
/ /dk/atira/pure/keywords/cohort_studies/netherlands_twin_register_ntr_
/ name=Netherlands Twin Register (NTR)
/ /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being
/ name=SDG 3 - Good Health and Well-being |
| Sprache: |
Englisch |
| Permalink: |
https://search.fid-benelux.de/Record/base-26843105 |
| Datenquelle: |
BASE;
Originalkatalog |
| Powered By: |
BASE |
| Link(s) :
|
https://research.vu.nl/en/publications/026ea12c-27db-4f5a-bc6d-f8d67ea37d82 |
