Human Prion Diseases in The Netherlands (1998-2009): Clinical, Genetic and Molecular Aspects
Prion diseases are rare and fatal neurodegenerative disorders that can be sporadic, inherited or acquired by infection. Based on a national surveillance program in the Netherlands we describe here the clinical, neuropathological, genetic and molecular characteristics of 162 patients with neuropathologically confirmed prion disease over a 12-year period (1998-2009). Since 1998, there has been a relatively stable mortality of Creutzfeldt-Jakob disease (CJD) in the Netherlands, ranging from 0.63 to 1.53 per million inhabitants per annum. Genetic analysis of the codon 129 methionine/valine (M/V) p... Mehr ...
Verfasser: |
Jansen, C
Parchi, P
Capellari, S
Verbaas, Carla
Schuur, Maaike
Strammiello, R
Corrado, P
Bishop, MT
van Gool, WA
Verbeek, MM
Baas, F
van Saane, W
Spliet, WGM
Jansen, GH
Duijn, Cornelia
Rozemuller, AJM |
Dokumenttyp: |
Artikel |
Erscheinungsdatum: |
2012 |
Reihe/Periodikum: |
Jansen , C , Parchi , P , Capellari , S , Verbaas , C , Schuur , M , Strammiello , R , Corrado , P , Bishop , MT , van Gool , WA , Verbeek , MM , Baas , F , van Saane , W , Spliet , WGM , Jansen , GH , Duijn , C & Rozemuller , AJM 2012 , ' Human Prion Diseases in The Netherlands (1998-2009): Clinical, Genetic and Molecular Aspects ' , PLoS One (print) , vol. 7 , no. 4 . https://doi.org/10.1371/journal.pone.0036333 |
Schlagwörter: |
/dk/atira/pure/keywords/researchprograms/AFL001000/EMCNIHES016402
/ name=EMC NIHES-01-64-02
/ /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being
/ name=SDG 3 - Good Health and Well-being |
Sprache: |
unknown |
Permalink: |
https://search.fid-benelux.de/Record/base-26840912 |
Datenquelle: |
BASE;
Originalkatalog |
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Link(s) :
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https://pure.eur.nl/en/publications/d4532676-7a7c-41b3-bf32-c7c19dd9ad87 |