Molecular diversity of Bacillus anthracis in the Netherlands: investigating the relationship to the wordwide population using whole-genome SNP discovery
Bacillus anthracis, the causative agent of anthrax, has been widely described as a clonal species. Here we report the use of both canonical SNP analysis and whole-genome sequencing to characterize the phylogenetic lineages of B. anthracis from the Netherlands. Eleven strains isolated over a 25-years period (1968–1993) were paired-end sequenced using parallel sequencing technology. Five canSNP groups or lineages, i.e. A.Br.001/002 (n = 6), A.Br.Aust94 (n = 2), A.Br.008/011 (n = 1), A.Br.011/009 (n = 1) and A.Br.Vollum (n = 1) were identified. Comparative analyses, with a focus on SNPs discovery... Mehr ...
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Dokumenttyp: | article/Letter to editor |
Erscheinungsdatum: | 2015 |
Schlagwörter: | Bacillus anthracis / Comparative genomics / High resolution melting (HRM) / Molecular typing / Single nucleotide polymorphism / Whole genome sequencing |
Sprache: | Englisch |
Permalink: | https://search.fid-benelux.de/Record/base-26838359 |
Datenquelle: | BASE; Originalkatalog |
Powered By: | BASE |
Link(s) : | https://research.wur.nl/en/publications/molecular-diversity-of-bacillus-anthracis-in-the-netherlands-inve |