Microbiome Analytics of the Gut Microbiota in Patients With Juvenile Idiopathic Arthritis : A Longitudinal Observational Cohort Study

OBJECTIVE: To assess the composition of gut microbiota in Italian and Dutch patients with juvenile idiopathic arthritis (JIA) at baseline, with inactive disease, and with persistent activity compared to healthy controls. METHODS: In a multicenter, prospective, observational cohort study, fecal samples were collected at baseline from 78 Italian and 21 Dutch treatment-naive JIA patients with <6 months of disease duration and compared to 107 geographically matched samples from healthy children. Forty-four follow-up samples from patients with inactive disease and 25 follow-up samples from patie... Mehr ...

Volltext
Verfasser: van Dijkhuizen, E. H.Pieter
Del Chierico, Federica
Malattia, Clara
Russo, Alessandra
Pires Marafon, Denise
ter Haar, Nienke M.
Magni-Manzoni, Silvia
Vastert, Sebastiaan J.
Dallapiccola, Bruno
Prakken, Berent
Martini, Alberto
De Benedetti, Fabrizio
Putignani, Lorenza
the Model Driven Paediatric European Digital Repository Consortium
Dokumenttyp: Artikel
Erscheinungsdatum: 2019
Schlagwörter: Arthritis / Juvenile/epidemiology / Case-Control Studies / Child / Preschool / Cohort Studies / Comorbidity / Dysbiosis/epidemiology / Faecalibacterium prausnitzii / Female / Firmicutes / Gastrointestinal Microbiome/genetics / Humans / Italy/epidemiology / Logistic Models / Longitudinal Studies / Male / Metagenomics / Netherlands/epidemiology / RNA / Ribosomal / 16S / Severity of Illness Index / Immunology and Allergy / Rheumatology / Immunology / Journal Article / Research Support / Non-U.S. Gov't / Observational Study
Sprache: Englisch
Permalink: https://search.fid-benelux.de/Record/base-26836181
Datenquelle: BASE; Originalkatalog
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Link(s) : https://dspace.library.uu.nl/handle/1874/392193