Minimally invasive versus open pancreatoduodenectomy (LEOPARD-2) : Study protocol for a randomized controlled trial
BACKGROUND: Data from observational studies suggest that minimally invasive pancreatoduodenectomy (MIPD) is superior to open pancreatoduodenectomy regarding intraoperative blood loss, postoperative morbidity, and length of hospital stay, without increasing total costs. However, several case-matched studies failed to demonstrate superiority of MIPD, and large registry studies from the USA even suggested increased mortality for MIPDs performed in low-volume (<10 MIPDs annually) centers. Randomized controlled multicenter trials are lacking but clearly required. We hypothesize that time to func... Mehr ...
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Dokumenttyp: | Artikel |
Erscheinungsdatum: | 2018 |
Schlagwörter: | Laparoscopic / Minimally invasive / Pancreatoduodenectomy / Robot-assisted / Whipple / Humans / Postoperative Complications/etiology / Treatment Outcome / Pancreatic Diseases/diagnosis / Pancreaticoduodenectomy/adverse effects / Recovery of Function / Randomized Controlled Trials as Topic / Clinical Trials / Phase III as Topic / Netherlands / Multicenter Studies as Topic / Time Factors / Laparoscopy/adverse effects / Phase II as Topic / Robotic Surgical Procedures/adverse effects / Pharmacology (medical) / Medicine (miscellaneous) / Journal Article |
Sprache: | Englisch |
Permalink: | https://search.fid-benelux.de/Record/base-26835693 |
Datenquelle: | BASE; Originalkatalog |
Powered By: | BASE |
Link(s) : | https://dspace.library.uu.nl/handle/1874/371905 |