Coumarin anticoagulants and co-trimoxazole: avoid the combination rather than manage the interaction
OBJECTIVE: The objective of our study was to examine the management of the interaction between acenocoumarol or phenprocoumon and several antibiotics by anticoagulation clinics and to compare the consequences of this interaction on users of co-trimoxazole with those for users of other antibiotics. METHODS: A follow-up study was conducted at four anticoagulation clinics in The Netherlands. Data on measurements of the International Normalised Ratio (INR), application of a preventive dose reduction (PDR) of the coumarin anticoagulant, fever and time within or outside the therapeutic INR range wer... Mehr ...
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Dokumenttyp: | Artikel |
Erscheinungsdatum: | 2007 |
Schlagwörter: | Aged / Anti-Bacterial Agents / Anticoagulants / Coumarins / Data Collection / Dose-Response Relationship / Drug / Drug Interactions / Female / Follow-Up Studies / Humans / International Normalized Ratio / Male / Multicenter Studies as Topic / Netherlands / Trimethoprim-Sulfamethoxazole Combination |
Sprache: | Englisch |
Permalink: | https://search.fid-benelux.de/Record/base-26835105 |
Datenquelle: | BASE; Originalkatalog |
Powered By: | BASE |
Link(s) : | https://dspace.library.uu.nl/handle/1874/319235 |