Risk estimates of dementia by apolipoprotein E genotypes from a population-based incidence study: the Rotterdam Study
OBJECTIVES: To provide risk estimates of dementia and Alzheimer disease as a function of the apolipoprotein E (APOE) genotypes and to assess the proportion of dementia that is attributable to the APOE genotypes. DESIGN: Case-control study nested in a population-based cohort study with a mean (SD) follow-up of 2.1 (0.9) years. SETTING: General population in Rotterdam, the Netherlands. PARTICIPANTS: A total of 134 patients with incident dementia and a random sample of 997 nondemented control subjects. No participant had dementia at baseline. MAIN OUTCOME MEASURES: Odds ratios for dementia and Al... Mehr ...
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Dokumenttyp: | Artikel |
Erscheinungsdatum: | 1998 |
Schlagwörter: | Aged / 80 and over / Alzheimer Disease/*epidemiology/genetics / Apolipoproteins E/*genetics / Case-Control Studies / Dementia/*epidemiology/genetics / Female / Genotype / Humans / Incidence / Male / Middle aged / Netherlands/epidemiology / Odds Ratio / Research Support / Non-U.S. Gov't / Risk Assessment |
Sprache: | Englisch |
Permalink: | https://search.fid-benelux.de/Record/base-26833221 |
Datenquelle: | BASE; Originalkatalog |
Powered By: | BASE |
Link(s) : | http://repub.eur.nl/pub/8867 |