Validity of the Mini-Mental State Examination-2 in Diagnosing Mild Cognitive Impairment and Dementia in Patients Visiting an Outpatient Clinic in the Netherlands

This study examined the utility of the recently published MMSE-2:SV in detecting cognitive impairment. We used receiver operating characteristics to test the discriminative power of the MMSE-2:SV for distinguishing between older adults without mild cognitive impairment (MCI) or dementia (n=67) and patients with MCI (n=76) or dementia (n=79). The results show that the MMSE-2:SV had excellent discriminative ability in distinguishing older controls from patients with dementia, with cut-off scores of 26 and 27 (max=30) yielding appropriate sensitivity (0.810 and 0.924, respectively) and specificit... Mehr ...

Verfasser: Sleutjes, Daan K.L.
Harmsen, Iris J.
van Bergen, Floor S.
Oosterman, Joukje M.
Dautzenberg, Paul L.J.
Kessels, Roy P.C.
Dokumenttyp: Artikel
Erscheinungsdatum: 2020
Reihe/Periodikum: Alzheimer Disease & Associated Disorders ; volume 34, issue 3, page 278-281 ; ISSN 0893-0341
Verlag/Hrsg.: Ovid Technologies (Wolters Kluwer Health)
Schlagwörter: Psychiatry and Mental health / Geriatrics and Gerontology / Gerontology / Clinical Psychology
Sprache: Englisch
Permalink: https://search.fid-benelux.de/Record/base-26832369
Datenquelle: BASE; Originalkatalog
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Link(s) : http://dx.doi.org/10.1097/wad.0000000000000403

This study examined the utility of the recently published MMSE-2:SV in detecting cognitive impairment. We used receiver operating characteristics to test the discriminative power of the MMSE-2:SV for distinguishing between older adults without mild cognitive impairment (MCI) or dementia (n=67) and patients with MCI (n=76) or dementia (n=79). The results show that the MMSE-2:SV had excellent discriminative ability in distinguishing older controls from patients with dementia, with cut-off scores of 26 and 27 (max=30) yielding appropriate sensitivity (0.810 and 0.924, respectively) and specificity (0.940 and 0.806). Discriminative power was close to good in distinguishing between older controls and patients with MCI. Here, however, no optimal cut-off point could be determined. Even though this study shows good sensitivity and adequate specificity for the MMSE-2:SV in discriminating individuals without MCI or dementia from those with dementia, its validity is limited for identifying patients with MCI.