Dietary intake of menaquinone is associated with a reduced risk of coronary heart disease: the Rotterdam Study
Vitamin K-dependent proteins, including matrix Gla-protein, have been shown to inhibit vascular calcification. Activation of these proteins via carboxylation depends on the availability of vitamin K. We examined whether dietary intake of phylloquinone (vitamin K-1) and menaquinone (vitamin K-2) were related to aortic calcification and coronary heart disease (CHD) in the population-based Rotterdam Study. The analysis included 4807 subjects with dietary data and no history of myocardial infarction at baseline (1990-1993) who were followed until January 1, 2000. The risk of incident CHD, all-caus... Mehr ...
Verfasser: | |
---|---|
Dokumenttyp: | Artikel |
Erscheinungsdatum: | 2004 |
Schlagwörter: | *Diet / Aortic Diseases/epidemiology / Arteriosclerosis/epidemiology / Calcinosis/epidemiology / Cholesterol/blood / Coronary Disease/epidemiology/*prevention & control / Energy Intake / Female / Humans / Lipoproteins / HDL Cholesterol/blood / Male / Middle aged / Mortality / Myocardial Infarction/mortality / Netherlands / Odds Ratio / Prospective Studies / Research Support / Non-U.S. Gov't / Risk Factors / Sex Characteristics / Vitamin K 1/administration & dosage / Vitamin K 2/*administration & dosage |
Sprache: | Englisch |
Permalink: | https://search.fid-benelux.de/Record/base-26831744 |
Datenquelle: | BASE; Originalkatalog |
Powered By: | BASE |
Link(s) : | http://repub.eur.nl/pub/10366 |