The main aim of this article is to investigate the management process in the transformation of industrial canal zones. This term is referred to those abandoned factory areas along watercourses that have made many areas at the edge of a consolidated urban structure quite distinctive. In the long-term process of transformation, managers from several parties participate in it with different titles and roles and have a very influential role. This article will investigate the efficiency level in the management processes and methods used in the transformation of such abandoned areas. Furthermore, it will explore the level of exchange between experimentation and practice so as to enhance and protect the qualities of these sites. The author will refer to B5 canal zones in The Netherlands as a case study. B5 or BrabantStad is the metropolitan area including the 5 cities (Eindhoven, Breda, Tilburg, s’ Hertogenbosch and Helmond) and the towns in-between, located in the southern area of the country, named Brabant. Former industrial zones located along specific canal-courses/shipways characterize all 5 Municipalities. Originally located at the edge of the historical urban structure of each city, these areas are characterized by industrial buildings of different scale and architectural styles. Furthermore, a system of navigable canals connects the 5 canal areas (and cities) in a circuit with a high potential. Methodologically, this paper will first discuss the meaning and heritage value of abandoned industrial canal zones, explaining the necessity to keep them standing and to protect their integrity. Secondly, it will illustrate the methods adopted in the management process of canal zone areas and will discuss the relationship between research and practice, focusing on the involvement and collaboration with Province, local authorities and University.