Macular thinning in prediabetes or type 2 diabetes without diabetic retinopathy:the Maastricht Study

Purpose: To assess macular thinning in individuals with prediabetes or type 2 diabetes without diabetic retinopathy (DM2 w/o DR) compared with individuals with normal glucose metabolism (NGM). Methods: Using spectral domain optical coherence tomography (SD-OCT), we measured macular thickness in six subfields as defined by the Early Treatment Diabetic Retinopathy Study (ETDRS) in 1838 participants from The Maastricht Study, a population-based cohort study (mean age 59 ± 8 years, 49% men, 1087 NGM, 279 prediabetes, 472 DM2 w/o DR). Multivariable linear regression was used to assess the associati... Mehr ...

Verfasser: De Clerck, Eline E.B.
Schouten, Jan S.A.G.
Berendschot, Tos T.J.M.
Goezinne, Fleur
Dagnelie, Pieter C.
Schaper, Nicolaas C.
Schram, Miranda T.
Stehouwer, Coen D.A.
Webers, Carroll A.B.
Dokumenttyp: Artikel
Erscheinungsdatum: 2018
Reihe/Periodikum: De Clerck , E E B , Schouten , J S A G , Berendschot , T T J M , Goezinne , F , Dagnelie , P C , Schaper , N C , Schram , M T , Stehouwer , C D A & Webers , C A B 2018 , ' Macular thinning in prediabetes or type 2 diabetes without diabetic retinopathy : the Maastricht Study ' , Acta Ophthalmologica , vol. 96 , no. 2 , pp. 174-182 . https://doi.org/10.1111/aos.13570
Schlagwörter: neurodegeneration / optical coherence tomography / retina / type 2 diabetes / Prospective Studies / Retinal Diseases/etiology / Tomography / Optical Coherence / Blood Glucose/metabolism / Humans / Middle Aged / Male / Diabetes Mellitus / Type 2/complications / Macula Lutea/pathology / Netherlands / Prediabetic State/complications / Female / Glycated Hemoglobin A/metabolism / Cohort Studies / Diabetic Retinopathy / /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being / name=SDG 3 - Good Health and Well-being
Sprache: Englisch
Permalink: https://search.fid-benelux.de/Record/base-26829284
Datenquelle: BASE; Originalkatalog
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Link(s) : https://research.tue.nl/en/publications/bf579531-9726-4f4e-afe2-e3bb46039773