Practical value of anti-xa activity in the evaluation of extracorporeal circuit anticoagulation during haemodialysis:Results of a cross-sectional single-centre study
Background/Aims: Anticoagulation of the extracorporeal circuit is essential for adequate haemodialysis (HD). Low molecular weight heparins (LMWHs) are safe and sufficient towards achieving this goal. In the Netherlands, dosage is based on bodyweight and adjusted based on clinical events. LMWH levels during dialysis can be quantified through measurement of the anti-Xa activity and a target range of 0.5-1.0 IU/mL has been proposed. We aimed to evaluate the practical value of the anti-Xa activity to guide LMWH dosage in HD patients. Additionally, the value of the activated partial thromboplastin... Mehr ...
| Verfasser: |
Coene, K.L.M.
Dekker, M.J.E.
Kerskes, M.C.H.M.
Hengst, M.
Schonck, M.J.M.
Konings, C.J.A.M.
Scharnhorst, V. |
| Dokumenttyp: |
Artikel |
| Erscheinungsdatum: |
2017 |
| Reihe/Periodikum: |
Coene , K L M , Dekker , M J E , Kerskes , M C H M , Hengst , M , Schonck , M J M , Konings , C J A M & Scharnhorst , V 2017 , ' Practical value of anti-xa activity in the evaluation of extracorporeal circuit anticoagulation during haemodialysis : Results of a cross-sectional single-centre study ' , Nephron , vol. 137 , no. 3 , pp. 205-211 . https://doi.org/10.1159/000479390 |
| Schlagwörter: |
Anti-Xa activity
/ Anticoagulation therapy
/ Haemodialysis
/ Cross-Sectional Studies
/ Heparin
/ Low-Molecular-Weight/therapeutic use
/ Humans
/ Middle Aged
/ Male
/ Anticoagulants/therapeutic use
/ Netherlands
/ Factor Xa Inhibitors/pharmacology
/ Partial Thromboplastin Time
/ Factor Xa/drug effects
/ Aged
/ 80 and over
/ Female
/ Kidney Failure
/ Chronic/physiopathology
/ Cohort Studies
/ Renal Dialysis |
| Sprache: |
Englisch |
| Permalink: |
https://search.fid-benelux.de/Record/base-26828969 |
| Datenquelle: |
BASE;
Originalkatalog |
| Powered By: |
BASE |
| Link(s) :
|
https://research.tue.nl/en/publications/198cbb0d-f34a-4883-bddc-dd2cabaa0a3d |
