Increasing incidence of group B streptococcus neonatal infections in the Netherlands is associated with clonal expansion of CC17 and CC23.
Group B streptococcus (GBS) is the leading cause of neonatal invasive disease worldwide. In the Netherlands incidence of the disease increased despite implementation of preventive guidelines. We describe a genomic analysis of 1345 GBS isolates from neonatal (age 0-89 days) invasive infections in the Netherlands reported between 1987 and 2016. Most isolates clustered into one of five major lineages: CC17 (39%), CC19 (25%), CC23 (18%), CC10 (9%) and CC1 (7%). There was a significant rise in the number of infections due to isolates from CC17 and CC23. Phylogenetic clustering analysis revealed tha... Mehr ...
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Dokumenttyp: | Artikel |
Erscheinungsdatum: | 2020 |
Verlag/Hrsg.: |
Springer Science and Business Media LLC
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Schlagwörter: | Bacterial Proteins / DNA / Bacterial / Female / Genomics / Humans / Incidence / Infant / Newborn / Male / Multilocus Sequence Typing / Netherlands / Phylogeny / Serogroup / Streptococcal Infections / Streptococcus |
Sprache: | Englisch |
Permalink: | https://search.fid-benelux.de/Record/base-26828786 |
Datenquelle: | BASE; Originalkatalog |
Powered By: | BASE |
Link(s) : | https://www.repository.cam.ac.uk/handle/1810/308721 |