The M-OVIN study: does switching treatment to FSH and / or IUI lead to higher pregnancy rates in a subset of women with world health organization type II anovulation not conceiving after six ovulatory cycles with clomiphene citrate - a randomised controlled trial
Background: Clomiphene citrate (CC) is first line treatment in women with World Health Organization (WHO) type II anovulation and polycystic ovary syndrome (PCOS). Whereas 60% to 85% of these women will ovulate on CC, only about one half will have conceived after six cycles. If women do not conceive, treatment can be continued with gonadotropins or intra-uterine insemination (IUI). At present, it is unclear for how many cycles ovulation induction with CC should be repeated, and when to switch to ovulation induction with gonadotropins and/or IUI. Methods/Design: We started a multicenter randomi... Mehr ...
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Dokumenttyp: | Journal article |
Erscheinungsdatum: | 2013 |
Verlag/Hrsg.: |
BioMed Central
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Schlagwörter: | Humans / Polycystic Ovary Syndrome / Anovulation / Infertility / Female / Clomiphene / Gonadotropins / Follicle Stimulating Hormone / Treatment Outcome / Insemination / Artificial / Ovulation Induction / Pregnancy Rate / Pregnancy / Netherlands / Time-to-Pregnancy |
Sprache: | Englisch |
Permalink: | https://search.fid-benelux.de/Record/base-26827857 |
Datenquelle: | BASE; Originalkatalog |
Powered By: | BASE |
Link(s) : | http://hdl.handle.net/2440/89269 |