Prescriptive contraceptive use among isotretinoin users in the Netherlands in comparison with non-users:a drug utilisation study

Purpose To assess the compliance with the isotretinoin Pregnancy Prevention Programme (PPP) by evaluating the use of prescribed contraceptives among isotretinoin users. The PPP contains a requirement for the use of contraceptive methods for women of childbearing potential. Methods A drug utilisation study was performed using data from a drug prescription database (containing Dutch community pharmacy data) covering a population of 500?000 patients. Contraceptive use in female isotretinoin users and in a reference group of female non-isotretinoin users (aged 1549?years) was compared using data f... Mehr ...