The American Psychiatric Association estimates that 3 to 7 per cent of all school aged children are diagnosed with attention deficit hyperactivity disorder (ADHD). Even after correcting for general cognitive ability, numerous studies report a negative association between ADHD and educational achievement. With polygenic scores we examined whether genetic variants that have a positive influence on educational attainment have a protective effect against ADHD. The effect sizes from a large GWA meta-analysis of educational attainment in adults were used to calculate polygenic scores in an independe... Mehr ...
| Verfasser: |
de Zeeuw, Eveline L.
van Beijsterveldt, Catharina E.M.
Glasner, Tina J.
Bartels, M.
Ehli, Erik A.
Davies, Gareth E.
Hudziak, James J.
Rietveld, Cornelius A.
Groen-Blokhuis, Maria M.
Hottenga, Jouke Jan
de Geus, Eco J.C.
Boomsma, Dorret I. |
| Dokumenttyp: |
Artikel |
| Erscheinungsdatum: |
2014 |
| Reihe/Periodikum: |
de Zeeuw , E L , van Beijsterveldt , C E M , Glasner , T J , Bartels , M , Ehli , E A , Davies , G E , Hudziak , J J , Rietveld , C A , Groen-Blokhuis , M M , Hottenga , J J , de Geus , E J C , Boomsma , D I & Social Science Genetic Assotiation Consortium 2014 , ' Polygenic scores associated with educational attainment in adults predict educational achievement and ADHD symptoms in children ' , American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics , vol. 165 , no. 6 , pp. 510-520 . https://doi.org/10.1002/ajmg.b.32254 |
| Schlagwörter: |
ADHD
/ Educational achievement
/ Genetics
/ Polygenic scores
/ School performance
/ academic achievement
/ achievement test
/ arithmetic
/ article
/ attention deficit disorder
/ attention disturbance
/ child
/ controlled study
/ educational status
/ effect size
/ gene frequency
/ gene linkage disequilibrium
/ genetic association
/ genetic variability
/ genotype
/ human
/ language
/ major clinical study
/ Netherlands
/ phenotype
/ priority journal
/ reading
/ single nucleotide polymorphism
/ study skills
/ symptom |
| Sprache: |
Englisch |
| Permalink: |
https://search.fid-benelux.de/Record/base-26826404 |
| Datenquelle: |
BASE;
Originalkatalog |
| Powered By: |
BASE |
| Link(s) :
|
https://hdl.handle.net/11370/c15eaa73-649e-4406-a53b-a09054506d03 |
