Changes in first-line cART regimens and short-term clinical outcome between 1996 and 2010 in The Netherlands
OBJECTIVES: Document progress in HIV-treatment in The Netherlands since 1996 by reviewing changing patterns of cART use and relating those to trends in patients' short-term clinical outcomes between 1996 and 2010. DESIGN AND METHODS: 1996-2010 data from 10,278 patients in the Dutch ATHENA national observational cohort were analysed. The annual number of patients starting a type of regimen was quantified. Trends in the following outcomes were described: i) recovery of 150 CD4 cells/mm(3) within 12 months of starting cART; ii) achieving viral load (VL) suppression ≤1,000 copies/ml within 12 mont... Mehr ...
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Dokumenttyp: | Artikel |
Erscheinungsdatum: | 2013 |
Reihe/Periodikum: | Smit , M , Smit , C , Geerlings , S E , Gras , L , Brinkman , K , Hallett , T B , de Wolf , F & ATHENA observational cohort 2013 , ' Changes in first-line cART regimens and short-term clinical outcome between 1996 and 2010 in The Netherlands ' , PLoS ONE , vol. 8 , no. 9 , e76071 . https://doi.org/10.1371/journal.pone.0076071 |
Schlagwörter: | Anti-Retroviral Agents / CD4 Lymphocyte Count / Cohort Studies / Drug Therapy / Combination / Female / HIV Infections / History / 20th Century / 21st Century / Humans / Kaplan-Meier Estimate / Male / Netherlands / Proportional Hazards Models / Treatment Outcome / Viral Load |
Sprache: | Englisch |
Permalink: | https://search.fid-benelux.de/Record/base-26826299 |
Datenquelle: | BASE; Originalkatalog |
Powered By: | BASE |
Link(s) : | https://hdl.handle.net/11370/b719ccb6-32db-4040-a48d-d5fa7439d62d |