Background Treatment choices for individual patients with an inborn bleeding disorder are increasingly challenging due to increasing options and rising costs for society. We have initiated an integrated interdisciplinary national research program. Objectives The SYMPHONY consortium strives to orchestrate personalized treatment in patients with an inborn bleeding disorder, by unraveling the mechanisms behind interindividual variations of bleeding phenotype. Patients The SYMPHONY consortium will investigate patients with an inborn bleeding disorder, both diagnosed and not yet diagnosed. Results... Mehr ...
| Verfasser: |
Cnossen, Marjon H.
van Moort, Iris
Reitsma, Simone H.
de Maat, Moniek P. M.
Schutgens, Roger E. G.
Urbanus, Rolf T.
Lingsma, Hester F.
Mathot, Ron A. A.
Gouw, Samantha C.
Meijer, Karina
Bredenoord, Annelien L.
van der Graaf, Rieke
Fijnvandraat, Karin
Meijer, Alexander B.
van den Akker, Emile
Bierings, Ruben
Eikenboom, Jeroen C. J.
van den Biggelaar, Maartje
de Haas, Masja
Voorberg, Jan
Leebeek, Frank W. G. |
| Dokumenttyp: |
Artikel |
| Erscheinungsdatum: |
2022 |
| Reihe/Periodikum: |
SYMPHONY Consortium , Cnossen , M H , van Moort , I , Reitsma , S H , de Maat , M P M , Schutgens , R E G , Urbanus , R T , Lingsma , H F , Mathot , R A A , Gouw , S C , Meijer , K , Bredenoord , A L , van der Graaf , R , Fijnvandraat , K , Meijer , A B , van den Akker , E , Bierings , R , Eikenboom , J C J , van den Biggelaar , M , de Haas , M , Voorberg , J & Leebeek , F W G 2022 , ' SYMPHONY consortium : Orchestrating personalized treatment for patients with bleeding disorders ' , Journal of Thrombosis and Haemostasis , vol. 20 , no. 9 , pp. 2001-2011 . https://doi.org/10.1111/jth.15778 |
| Schlagwörter: |
bleeding disorders
/ cellular models
/ personalized treatment
/ pharmacokinetics
/ proteomics
/ value-based health care
/ GENE-THERAPY
/ INHIBITOR DEVELOPMENT
/ HEMOPHILIA
/ GENERATION
/ COAGULATION
/ NETHERLANDS
/ PHENOTYPE
/ MUTATION
/ DISEASE
/ RISK |
| Sprache: |
Englisch |
| Permalink: |
https://search.fid-benelux.de/Record/base-26825820 |
| Datenquelle: |
BASE;
Originalkatalog |
| Powered By: |
BASE |
| Link(s) :
|
https://hdl.handle.net/11370/847c2f16-1d4c-4a97-8195-167c1b87a997 |
