Within the Netherlands a national network of biobanks has been established (Biobanking and Biomolecular Research Infrastructure-Netherlands (BBMRI-NL)) as a national node of the European BBMRI. One of the aims of BBMRI-NL is to enrich biobanks with different types of molecular and phenotype data. Here, we describe the Genome of the Netherlands (GoNL), one of the projects within BBMRI-NL. GoNL is a whole-genome-sequencing project in a representative sample consisting of 250 trio-families from all provinces in the Netherlands, which aims to characterize DNA sequence variation in the Dutch popula... Mehr ...
| Verfasser: |
Boomsma, Dorret I.
Wijmenga, Cisca
Slagboom, Eline P.
Swertz, Morris A.
Karssen, Lennart C.
Abdellaoui, Abdel
Ye, Kai
Guryev, Victor
Vermaat, Martijn
van Dijk, Freerk
Francioli, Laurent C.
Hottenga, Jouke Jan
Laros, Jeroen F. J.
Li, Qibin
Li, Yingrui
Cao, Hongzhi
Chen, Ruoyan
Du, Yuanping
Li, Ning
Cao, Sujie
van Setten, Jessica
Menelaou, Androniki
Pulit, Sara L.
Hehir-Kwa, Jayne Y.
Beekman, Marian
Elbers, Clara C.
Byelas, Heorhiy
de Craen, Anton J. M.
Deelen, Patrick
Dijkstra, Martijn
den Dunnen, Johan T.
de Knijff, Peter
Houwing-Duistermaat, Jeanine
Koval, Vyacheslav
Estrada, Karol
Hofman, Albert
Kanterakis, Alexandros
van Enckevort, David
Mai, Hailiang
Kattenberg, Mathijs
van Leeuwen, Elisabeth M.
Neerincx, Pieter B. T.
Oostra, Ben
Rivadeneira, Fernanodo
Suchiman, Eka H. D.
Uitterlinden, Andre G.
Willemsen, Gonneke
Wolffenbuttel, Bruce H.
Wang, Jun
de Bakker, Paul I. W.
van Ommen, Gert-Jan
van Duijn, Cornelia M. |
| Dokumenttyp: |
Artikel |
| Erscheinungsdatum: |
2014 |
| Reihe/Periodikum: |
Boomsma , D I , Wijmenga , C , Slagboom , E P , Swertz , M A , Karssen , L C , Abdellaoui , A , Ye , K , Guryev , V , Vermaat , M , van Dijk , F , Francioli , L C , Hottenga , J J , Laros , J F J , Li , Q , Li , Y , Cao , H , Chen , R , Du , Y , Li , N , Cao , S , van Setten , J , Menelaou , A , Pulit , S L , Hehir-Kwa , J Y , Beekman , M , Elbers , C C , Byelas , H , de Craen , A J M , Deelen , P , Dijkstra , M , den Dunnen , J T , de Knijff , P , Houwing-Duistermaat , J , Koval , V , Estrada , K , Hofman , A , Kanterakis , A , van Enckevort , D , Mai , H , Kattenberg , M , van Leeuwen , E M , Neerincx , P B T , Oostra , B , Rivadeneira , F , Suchiman , E H D , Uitterlinden , A G , Willemsen , G , Wolffenbuttel , B H , Wang , J , de Bakker , P I W , van Ommen , G-J & van Duijn , C M 2014 , ' The Genome of the Netherlands : design, and project goals ' , European Journal of Human Genetics , vol. 22 , no. 2 , pp. 221-227 . https://doi.org/10.1038/ejhg.2013.118 |
| Schlagwörter: |
whole-genome sequence
/ trio-design
/ population genetics
/ SUSCEPTIBILITY VARIANTS
/ WIDE ASSOCIATION
/ COMMON SNPS
/ HERITABILITY
/ DISEASE
/ TWIN
/ MUTATIONS
/ FAMILY
/ RISK |
| Sprache: |
Englisch |
| Permalink: |
https://search.fid-benelux.de/Record/base-26825811 |
| Datenquelle: |
BASE;
Originalkatalog |
| Powered By: |
BASE |
| Link(s) :
|
https://hdl.handle.net/11370/831fe563-6d71-4e04-874d-45e8ff4bc078 |
