Economic evaluation of apixaban for the prevention of stroke in non-valvular atrial fibrillation in the Netherlands
BACKGROUND: Stroke prevention is the main goal of treating patients with atrial fibrillation (AF). Vitamin-K antagonists (VKAs) present an effective treatment in stroke prevention, however, the risk of bleeding and the requirement for regular coagulation monitoring are limiting their use. Apixaban is a novel oral anticoagulant associated with significantly lower hazard rates for stroke, major bleedings and treatment discontinuations, compared to VKAs. OBJECTIVE: To estimate the cost-effectiveness of apixaban compared to VKAs in non-valvular AF patients in the Netherlands. METHODS: Previously p... Mehr ...
| Verfasser: |
Stevanovic, Jelena
Pompen, Marjolein
Le, Hoa H.
Rozenbaum, Mark H.
Tieleman, Robert G.
Postma, Maarten J. |
| Dokumenttyp: |
Artikel |
| Erscheinungsdatum: |
2014 |
| Reihe/Periodikum: |
Stevanovic , J , Pompen , M , Le , H H , Rozenbaum , M H , Tieleman , R G & Postma , M J 2014 , ' Economic evaluation of apixaban for the prevention of stroke in non-valvular atrial fibrillation in the Netherlands ' , PLoS ONE , vol. 9 , no. 8 , e103974 . https://doi.org/10.1371/journal.pone.0103974 |
| Schlagwörter: |
NCT00412984
/ NCT00496769
/ acenocoumarol
/ acetylsalicylic acid
/ antivitamin K
/ apixaban
/ phenprocoumon
/ warfarin
/ adult
/ aged
/ anticoagulation
/ article
/ bleeding
/ brain hemorrhage
/ brain ischemia
/ cerebrovascular accident
/ clinical article
/ controlled study
/ cost effectiveness analysis
/ diabetes mellitus
/ drug cost
/ economic evaluation
/ female
/ gastrointestinal hemorrhage
/ health care cost
/ heart atrium fibrillation
/ heart failure
/ heart infarction
/ human
/ hypertension
/ international normalized ratio
/ male
/ Netherlands
/ non valvular heart atrium fibrillation
/ quality adjusted life year
/ quality of life
/ sensitivity analysis
/ thromboembolism |
| Sprache: |
Englisch |
| Permalink: |
https://search.fid-benelux.de/Record/base-26824773 |
| Datenquelle: |
BASE;
Originalkatalog |
| Powered By: |
BASE |
| Link(s) :
|
https://hdl.handle.net/11370/22ccec7f-b1cb-483d-85cf-52029f211bba |
