BACKGROUND: Major depressive disorder (MDD) is a common mood disorder, with a heritability of around 34%. Molecular genetic studies made significant progress and identified genetic markers associated with the risk of MDD; however, progress is slowed down by substantial heterogeneity as MDD is assessed differently across international cohorts. Here, we used a standardized online approach to measure MDD in multiple cohorts in the Netherlands and evaluated whether this approach can be used in epidemiological and genetic association studies of depression. METHODS: Within the Biobank Netherlands In... Mehr ...
| Verfasser: |
Fedko, Iryna O
Hottenga, Jouke-Jan
Helmer, Quinta
Mbarek, Hamdi
Huider, Floris
Amin, Najaf
Beulens, Joline W
Bremmer, Marijke A
Elders, Petra J
Galesloot, Tessel E
Kiemeney, Lambertus A
van Loo, Hanna M
Picavet, H Susan J
Rutters, Femke
van der Spek, Ashley
van de Wiel, Anne M
van Duijn, Cornelia
de Geus, Eco J C
Feskens, Edith J M
Hartman, Catharina A
Oldehinkel, Albertine J
Smit, Jan H
Verschuren, W M Monique
Penninx, Brenda W J H
Boomsma, Dorret I
Bot, Mariska |
| Dokumenttyp: |
Artikel |
| Erscheinungsdatum: |
2021 |
| Reihe/Periodikum: |
Fedko , I O , Hottenga , J-J , Helmer , Q , Mbarek , H , Huider , F , Amin , N , Beulens , J W , Bremmer , M A , Elders , P J , Galesloot , T E , Kiemeney , L A , van Loo , H M , Picavet , H S J , Rutters , F , van der Spek , A , van de Wiel , A M , van Duijn , C , de Geus , E J C , Feskens , E J M , Hartman , C A , Oldehinkel , A J , Smit , J H , Verschuren , W M M , Penninx , B W J H , Boomsma , D I & Bot , M 2021 , ' Measurement and genetic architecture of lifetime depression in the Netherlands as assessed by LIDAS (Lifetime Depression Assessment Self-report) ' , Psychological Medicine , vol. 51 , no. 8 , pp. 1345–1354 . https://doi.org/10.1017/S0033291720000100 |
| Sprache: |
Englisch |
| Permalink: |
https://search.fid-benelux.de/Record/base-26824508 |
| Datenquelle: |
BASE;
Originalkatalog |
| Powered By: |
BASE |
| Link(s) :
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https://hdl.handle.net/11370/1041d328-6fd8-4d1a-aac1-4dcc44375233 |
