The duration of effect of infliximab maintenance treatment in paediatric Crohn's disease is limited.

Background Infliximab is effective for induction and maintenance of remission in children with moderately to severely active Crohn's disease (CD). Aim To evaluate the long-term efficacy of infliximab treatment in paediatric CD. Methods In this observational, multicentre study, all paediatric CD patients in The Netherlands treated with infliximab from October 1992 to November 2009 and with minimal follow-up of 3 months since start of infliximab, were studied. Results One hundred and fifty-two CD patients [81M; median age at start of infliximab 15.0 years (IQR 13.1-16.4)] received a median numbe... Mehr ...

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Verfasser: De Bie, C.I.
Hummel, T.Z.
Kindermann, A.
Kokke, F.T.
Damen, G.M.
Kneepkens, C.M.
Van Rheenen, P.F.
Schweizer, J.J.
Hoekstra, J.H.
Norbruis, O.F.
Tjon, A.T.W.E.
Vreugdenhil, A.C.E.
Deckers Kocken, J.M.
Gijsbers, C.F.
Escher, J.C.
De Ridder, L.
Dokumenttyp: Artikel
Erscheinungsdatum: 2011
Reihe/Periodikum: De Bie , C I , Hummel , T Z , Kindermann , A , Kokke , F T , Damen , G M , Kneepkens , C M , Van Rheenen , P F , Schweizer , J J , Hoekstra , J H , Norbruis , O F , Tjon , A T W E , Vreugdenhil , A C E , Deckers Kocken , J M , Gijsbers , C F , Escher , J C & De Ridder , L 2011 , ' The duration of effect of infliximab maintenance treatment in paediatric Crohn's disease is limited. ' , Alimentary Pharmacology & Therapeutics , vol. 33 , no. 2 , pp. 243-250 . https://doi.org/10.1111/j.1365-2036.2010.04507.x
Schlagwörter: INFLAMMATORY-BOWEL-DISEASE / SHORT-TERM / THERAPY / CHILDREN / ANTIBODY / SAFETY / EFFICACY / COHORT / NETHERLANDS / EXPERIENCE
Sprache: Englisch
Permalink: https://search.fid-benelux.de/Record/base-26821905
Datenquelle: BASE; Originalkatalog
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Link(s) : https://cris.maastrichtuniversity.nl/en/publications/aaf983dd-2884-4d60-9ab8-4b487018ae87