Background: Although surgical resection has been considered the only curative option for colorectal liver metastases (CLM), thermal ablation has recently been suggested as an alternative curative treatment. A prospective randomised trial is required to define the efficacy of resection vs ablation for the treatment of colorectal liver metastases. Methods: Design and setting: This is a multicentre, open, randomised controlled non-inferiority trial design with internal pilot and will be performed in tertiary liver centres in UK and The Netherlands. Participants: Eligible patients will be those wi... Mehr ...
| Verfasser: |
Gurusamy, Kurinchi
Corrigan, Neil
Croft, Julie
Twiddy, Maureen
Morris, Stephen
Woodward, Nick
Bandula, Steve
Hochhauser, Daniel
Napp, Vicky
Pullan, Alison
Jakowiw, Nicholas
Prasad, Raj
Damink, Steven Olde
van Laarhoven, C. J. H. M.
de Wilt, Johannes H. W.
Brown, Julia
Davidson, Brian R. |
| Dokumenttyp: |
Artikel |
| Erscheinungsdatum: |
2018 |
| Reihe/Periodikum: |
Gurusamy , K , Corrigan , N , Croft , J , Twiddy , M , Morris , S , Woodward , N , Bandula , S , Hochhauser , D , Napp , V , Pullan , A , Jakowiw , N , Prasad , R , Damink , S O , van Laarhoven , C J H M , de Wilt , J H W , Brown , J & Davidson , B R 2018 , ' Liver resection surgery versus thermal ablation for colorectal LiVer MetAstases (LAVA) : study protocol for a randomised controlled trial ' , Trials , vol. 19 , 105 . https://doi.org/10.1186/s13063-018-2499-5 |
| Schlagwörter: |
Randomised controlled trial
/ Cost-benefit analysis
/ Liver
/ Neoplasm metastasis
/ Colorectal neoplasms
/ Hepatectomy
/ Ablation techniques
/ RADIOFREQUENCY ABLATION
/ MICROWAVE ABLATION
/ HEPATIC METASTASES
/ SURGICAL COMPLICATIONS
/ 2-STAGE HEPATECTOMY
/ COST-EFFECTIVENESS
/ CANCER
/ MANAGEMENT
/ OUTCOMES
/ CLASSIFICATION
/ Prospective Studies
/ Humans
/ Pragmatic Clinical Trials as Topic
/ Hepatectomy/adverse effects
/ Netherlands
/ Multicenter Studies as Topic
/ Time Factors
/ Chemotherapy
/ Adjuvant
/ Microwaves/adverse effects
/ Equivalence Trials as Topic
/ Postoperative Complications/etiology
/ Treatment Outcome
/ United Kingdom
/ Colorectal Neoplasms/mortality
/ Disease-Free Survival
/ Radiofrequency Ablation/adverse effects
/ Pilot Projects
/ Liver Neoplasms/mortality |
| Sprache: |
Englisch |
| Permalink: |
https://search.fid-benelux.de/Record/base-26821503 |
| Datenquelle: |
BASE;
Originalkatalog |
| Powered By: |
BASE |
| Link(s) :
|
https://cris.maastrichtuniversity.nl/en/publications/5e8c5432-a611-48a4-b6a8-2b1c8ebf84aa |
