OBJECTIVES: Rotavirus vaccination has 87% to 100% effectiveness against severe rotavirus acute gastroenteritis (AGE) in healthy infants in high-income countries. Little is known whether infants with medical risk conditions (MRCs) are equally protected and if the vaccine is equally well tolerated. We conducted a quasi-experimental prospective multicenter before-after cohort study to assess the vaccine effectiveness (VE) and safety profile of the human rotavirus vaccine (HRV) among MRC infants that required prolonged or frequent postnatal care. METHODS: The Netherlands has no national rotavirus... Mehr ...
| Verfasser: |
van Dongen, Josephine A P
Rouers, Elsbeth D M
Schuurman, Rob
Band, Caterina
Watkins, Shannon M
van Houten, Marlies A
Bont, Louis J
Norbruis, Obbe F
Hemels, Marieke A C
van Well, Gijs T J
Vlieger, Arine M
van der Sluijs, Jacqueline
Stas, Helene G
Tramper-Stranders, Gerdien
Kleinlugtenbeld, Elly A
van Kempen, Anne A M W
Wessels, Margreet
van Rossem, Maaike C
Dassel, Carin A C M
Pajkrt, Dasja
Bonten, Marc J M
Bruijning-Verhagen, Patricia C J |
| Dokumenttyp: |
Artikel |
| Erscheinungsdatum: |
2021 |
| Reihe/Periodikum: |
van Dongen , J A P , Rouers , E D M , Schuurman , R , Band , C , Watkins , S M , van Houten , M A , Bont , L J , Norbruis , O F , Hemels , M A C , van Well , G T J , Vlieger , A M , van der Sluijs , J , Stas , H G , Tramper-Stranders , G , Kleinlugtenbeld , E A , van Kempen , A A M W , Wessels , M , van Rossem , M C , Dassel , C A C M , Pajkrt , D , Bonten , M J M & Bruijning-Verhagen , P C J 2021 , ' Rotavirus Vaccine Safety and Effectiveness in Infants With High-Risk Medical Conditions ' , Pediatrics , vol. 148 , no. 6 , 2021051901 . https://doi.org/10.1542/peds.2021-051901 |
| Schlagwörter: |
Congenital Abnormalities/epidemiology
/ Controlled Before-After Studies
/ Female
/ Gastroenteritis/epidemiology
/ Hospitalization/statistics & numerical data
/ Humans
/ Infant
/ Premature
/ Small for Gestational Age
/ Male
/ Netherlands/epidemiology
/ Prospective Studies
/ Rotavirus Infections/epidemiology
/ Rotavirus Vaccines/administration & dosage
/ Vaccination Coverage
/ Vaccine Efficacy
/ EFFICACY
/ GASTROENTERITIS
/ CHILDREN
/ IMMUNOGENICITY
/ DISEASE
/ BURDEN |
| Sprache: |
Englisch |
| Permalink: |
https://search.fid-benelux.de/Record/base-26821343 |
| Datenquelle: |
BASE;
Originalkatalog |
| Powered By: |
BASE |
| Link(s) :
|
https://cris.maastrichtuniversity.nl/en/publications/41afde0d-f175-4368-8d2f-2b481e54dde7 |
