Polymorphisms in genes of the renin-angiotensin-aldosterone system and renal cell cancer risk: Interplay with hypertension and intakes of sodium, potassium and fluid
Hypertension is an established risk factor for renal cell cancer (RCC). The renin-angiotensin-aldosterone system (RAAS) regulates blood pressure and is closely linked to hypertension. RAAS additionally influences homeostasis of electrolytes (e.g. sodium and potassium) and fluid. We investigated single nucleotide polymorphisms (SNPs) in RAAS and their interactions with hypertension and intakes of sodium, potassium and fluid regarding RCC risk in the Netherlands Cohort Study (NLCS), which was initiated in 1986 and included 120,852 participants aged 55-69 years. Diet and lifestyle were assessed b... Mehr ...
Verfasser: |
Deckers, I.A.
van den Brandt, P.A.
van Engeland, M.
van Schooten, F.J.
Godschalk, R.W.
Keszei, A.P.
Schouten, L.J. |
Dokumenttyp: |
Artikel |
Erscheinungsdatum: |
2015 |
Reihe/Periodikum: |
Deckers , I A , van den Brandt , P A , van Engeland , M , van Schooten , F J , Godschalk , R W , Keszei , A P & Schouten , L J 2015 , ' Polymorphisms in genes of the renin-angiotensin-aldosterone system and renal cell cancer risk: Interplay with hypertension and intakes of sodium, potassium and fluid ' , International Journal of Cancer , vol. 136 , no. 5 , pp. 1104-1116 . https://doi.org/10.1002/ijc.29060 |
Schlagwörter: |
Diet
/ hypertension
/ polymorphism
/ renal cell cancer risk
/ renin-angiotensin-aldosterone system
/ SCALE PROSPECTIVE COHORT
/ BLOOD-PRESSURE
/ NETHERLANDS COHORT
/ METAANALYSIS
/ ASSOCIATION
/ DISEASE
/ QUESTIONNAIRE
/ EPISTASIS
/ CARCINOMA |
Sprache: |
Englisch |
Permalink: |
https://search.fid-benelux.de/Record/base-26821052 |
Datenquelle: |
BASE;
Originalkatalog |
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Link(s) :
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https://cris.maastrichtuniversity.nl/en/publications/1a0a0a9e-97ee-4fb7-b941-09a228629187 |