Strong associations and moderate predictive value of early symptoms for SARS-CoV-2 test positivity among healthcare workers, the Netherlands, March 2020

Healthcare workers (n = 803) with mild symptoms were tested for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (n = 90 positive) and asked to complete a symptom questionnaire. Anosmia, muscle ache, ocular pain, general malaise, headache, extreme tiredness and fever were associated with positivity. A predictive model based on these symptoms showed moderate discriminative value (sensitivity: 91.2%; specificity: 55.6%). While our models would not justify presumptive SARS-CoV-2 diagnosis without molecular confirmation, it can contribute to targeted screening strategies.

Verfasser: Tostmann, A
Bradley, J
Bousema, T
Yiek, W-K
Holwerda, M
Bleeker-Rovers, C
Ten Oever, J
Meijer, C
Rahamat-Langendoen, J
Hopman, J
van der Geest-Blankert, N
Wertheim, H
Dokumenttyp: Journal article
Erscheinungsdatum: 2021
Verlag/Hrsg.: European Centre for Disease Prevention and Control
Sprache: Englisch
Permalink: https://search.fid-benelux.de/Record/base-26820864
Datenquelle: BASE; Originalkatalog
Powered By: BASE
Link(s) : https://doi.org/10.2807/1560-7917.es.2020.25.16.2000508