Diagnostic accuracy of CT for local staging of colon cancer:A nationwide study in the Netherlands

Objective: To determine the accuracy of computed tomography (CT)-based staging in selecting high-risk colon cancer patients who would benefit from neoadjuvant chemotherapy while avoiding overtreatment. Methods: Data of adult patients diagnosed with non-metastatic primary colon cancer in 2005–2020, who underwent surgical resection without neoadjuvant chemotherapy, were retrospectively collected from the Netherlands Cancer Registry. Agreement between clinical and pathological evaluation for each T and N stage was calculated. Sensitivity and specificity analyses were conducted to predict T3-T4 an... Mehr ...