Measurements of medial temporal lobe atrophy for prediction of Alzheimer's disease in subjects with mild cognitive impairment
Our aim was to compare the predictive accuracy of 4 different medial temporal lobe measurements for Alzheimer's disease (AD) in subjects with mild cognitive impairment (MCI). Manual hippocampal measurement, automated atlas-based hippocampal measurement, a visual rating scale (MTA-score), and lateral ventricle measurement were compared. Predictive accuracy for AD 2 years after baseline was assessed by receiver operating characteristics analyses with area under the curve as outcome. Annual cognitive decline was assessed by slope analyses up to 5 years after baseline. Correlations with biomarkers... Mehr ...
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Dokumenttyp: | Artikel |
Erscheinungsdatum: | 2013 |
Schlagwörter: | Netherlands / Aurora Universities Network / SP1-Cooperation / EC / FP7 / European Commission / Food / Agriculture and Fisheries / and Biotechnology / Geriatrics and Gerontology / Developmental Biology / Neurology (clinical) / Aging / General Neuroscience |
Sprache: | Englisch |
Permalink: | https://search.fid-benelux.de/Record/base-26811752 |
Datenquelle: | BASE; Originalkatalog |
Powered By: | BASE |
Link(s) : | https://www.openaccessrepository.it/record/86681 |