Gallbladder histopathology during murine gallstone formation: Relation to motility and concentrating function
C57L mice are susceptible and AKR mice are resistant to gallstone formation. We studied in male mice of both strains gallbladder histopathology, cholecystokinin-induced emptying, and concentrating function at 0, 14, 28, and 56 days on a lithogenic diet. Gallbladder wall thickness increased on the diet, with stromal granulocyte infiltration, progressive fibrosis, edema, and epithelial cell indentation, particularly in C57L. Strong basal cholecystokinin octapeptide-induced gallbladder emptying (70% of fasting volumes) occurred in both strains, but fasting gallbladder volumes were significantly l... Mehr ...
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Dokumenttyp: | Artikel |
Erscheinungsdatum: | 2006 |
Schlagwörter: | Netherlands / Cell Biology / Endocrinology / Biochemistry |
Sprache: | Englisch |
Permalink: | https://search.fid-benelux.de/Record/base-26811491 |
Datenquelle: | BASE; Originalkatalog |
Powered By: | BASE |
Link(s) : | https://www.openaccessrepository.it/record/110199 |