Effect of early intensive multifactorial therapy on 5-year cardiovascular outcomes in individuals with type 2 diabetes detected by screening (ADDITION-Europe): a cluster-randomised trial.
Background Intensive treatment of multiple cardiovascular risk factors can halve mortality among people with established type 2 diabetes. We investigated the effect of early multifactorial treatment after diagnosis by screening. Methods In a pragmatic, cluster-randomised, parallel-group trial done in Denmark, the Netherlands, and the UK, 343 general practices were randomly assigned screening of registered patients aged 40–69 years without known diabetes followed by routine care of diabetes or screening followed by intensive treatment of multiple risk factors. The primary endpoint was first car... Mehr ...
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Dokumenttyp: | Journal article |
Erscheinungsdatum: | 2012 |
Verlag/Hrsg.: |
Elsevier
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Schlagwörter: | Aged / Cluster Analysis / Denmark / Diabetes Mellitus / Type 2 / Diabetic Angiopathies / Female / Great Britain / Humans / Hypoglycemic Agents / Intention to Treat Analysis / Male / Mass Screening / Middle Aged / Netherlands / Outcome Assessment (Health Care) / Risk Factors |
Sprache: | Englisch |
Permalink: | https://search.fid-benelux.de/Record/base-26809500 |
Datenquelle: | BASE; Originalkatalog |
Powered By: | BASE |
Link(s) : | http://hdl.handle.net/2381/23715 |