Variability and pathogenicity of hepatitis E virus genotype 3 variants
Infection with hepatitis E virus (HEV) can be clinically inapparent or produce symptoms and signs of hepatitis of varying severity and occasional fatality. This variability in clinical outcomes may reflect differences in host susceptibility or the presence of virally encoded determinants of pathogenicity. Analysis of complete genome sequences supports the division of HEV genotype 3 (HEV-3) variants into three major clades: 3ra comprising HEV isolates from rabbits, and 3efg and 3abchij comprising the corresponding named subtypes derived from humans and pigs. Using this framework, we investigate... Mehr ...
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Dokumenttyp: | Journal article |
Erscheinungsdatum: | 2015 |
Verlag/Hrsg.: |
Microbiology Society
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Schlagwörter: | Science & Technology / Life Sciences & Biomedicine / Biotechnology & Applied Microbiology / Virology / GERMAN BLOOD-DONORS / PHYLOGENETIC ANALYSIS / FULMINANT-HEPATITIS / GENETIC-VARIABILITY / FAMILY HEPEVIRIDAE / DISEASE SEVERITY / INFECTION / CLASSIFICATION / RECOMBINATION / TRANSMISSION / France / Genetic Variation / Germany / Hepatitis E / Hepatitis E virus / Humans / Molecular Sequence Data / Netherlands / Phylogeny / Scotland / Virulence |
Sprache: | Englisch |
Permalink: | https://search.fid-benelux.de/Record/base-26808170 |
Datenquelle: | BASE; Originalkatalog |
Powered By: | BASE |
Link(s) : | http://hdl.handle.net/10044/1/81487 |