Profiles and motives for PGD: a prospective cohort study of couples referred for PGD in the Netherlands

BACKGROUND PGD is nowadays a well-established alternative to prenatal diagnosis. However, information with respect to couples’ motives and profiles for choosing PGD is scarce. METHODS A prospective cohort of 264 couples referred for PGD was interviewed semi-structurally after intake, and follow-up data were collated after 6–8 years. Outcome measures were: the primary choice shortly after intake (PGD intention), and their definitive use, until maximum 8 years later (PGD use). Logistic regression analysis was performed with clinical impact of the genetic disorder, couples’ experiences, obstetric... Mehr ...