Outcome of BRCA1- compared with BRCA2-associated ovarian cancer: a nationwide study in the Netherlands
Background Recent studies suggested an improved overall survival (OS) for BRCA2 - versus BRCA1 -associated epithelial ovarian cancer (EOC), whereas the impact of chemotherapy is not yet clear. In a nationwide cohort, we examined the results of primary treatment, progression-free survival (PFS), treatment-free interval (TFI), and OS of BRCA1 versus BRCA2 EOC patients. Methods Two hundred and forty-five BRCA1 - and 99 BRCA2 -associated EOC patients were identified through all Dutch university hospitals. Analyses were carried out with the Pearson's Chi-square test, Kaplan–Meier, and Cox regressio... Mehr ...
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Dokumenttyp: | TEXT |
Erscheinungsdatum: | 2013 |
Verlag/Hrsg.: |
Oxford University Press
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Schlagwörter: | Original article |
Sprache: | Englisch |
Permalink: | https://search.fid-benelux.de/Record/base-26806120 |
Datenquelle: | BASE; Originalkatalog |
Powered By: | BASE |
Link(s) : | http://annonc.oxfordjournals.org/cgi/content/short/mdt068v1 |