Experiences of and recommendations on clinical trial design in Alzheimer’s disease from the participant’s point of view: a mixed-methods study in two clinical trial centers in the Netherlands

Abstract Introduction In the context of the development of pharmaceutical interventions, expectations and experiences of participants are essential. Their insights may be particularly helpful to address the challenges of recruiting and retaining participants for Alzheimer’s disease (AD) clinical trials. We examined clinical trial participants’ experiences to optimize trial design in Alzheimer’s disease (AD). Method In this mixed-methods study, we included adults who participated in sponsor-initiated AD trials at Brain Research Center, a clinical trial organization in the Netherlands. Participa... Mehr ...

Verfasser: Lois Ottenhoff
Everard G. B. Vijverberg
Leonie N. C. Visser
Merike Verijp
Niels D. Prins
Wiesje M. Van der Flier
Sietske A. M. Sikkes
Dokumenttyp: Artikel
Erscheinungsdatum: 2023
Reihe/Periodikum: Alzheimer’s Research & Therapy, Vol 15, Iss 1, Pp 1-12 (2023)
Verlag/Hrsg.: BMC
Schlagwörter: Alzheimer’s disease / Mild cognitive impairment / Engagement in research trials / Patients / Qualitative research / Quantitative research / Neurosciences. Biological psychiatry. Neuropsychiatry / RC321-571 / Neurology. Diseases of the nervous system / RC346-429
Sprache: Englisch
Permalink: https://search.fid-benelux.de/Record/base-26804892
Datenquelle: BASE; Originalkatalog
Powered By: BASE
Link(s) : https://doi.org/10.1186/s13195-023-01190-0