Molecular Epidemiological Screening of the Genome of the Strain Coxiella burnetii NL3262 (Netherlands, 2009) Using Formal Order Analysis

Background. More than 4,000 cases of acute disease in humans were reported during the mass Q fever outbreak in the Netherlands in 2007–2010. The Coxiella burnetii NL3262 strain was isolated during this outbreak from an aborted placenta of a goat and was studied using means of molecular biology and bioinformation techniques. Goals. Approbation of a new bioinformatics approach – formal order analysis – to study the origin of the strains that caused a massive outbreak of Q fever in the Netherlands using the C. burnetii NL3262 strain. Methodology. New tools of the formal order analysis (FOA) «Map... Mehr ...