An Updated Analysis of the Impact of HPV Vaccination Based on Long-term Effectiveness in the Netherlands

Abstract Introduction Vaccination against human papillomavirus (HPV) is considered the most effective strategy to protect women from cervical cancer. Three HPV vaccines are currently licensed in Europe and, although they are generally supported by favorable health economic outcomes, current models fall short in predicting vaccination benefits. Here, we aim to re-evaluate the health benefits of HPV vaccination, using updated long-term effectiveness data and emphasizing quality of life losses related to pre-cancer disease and treatment. Methods We used a static Markov model that compared “only s... Mehr ...