Dynamics in Prophage Content of Invasive and Noninvasive M1 and M28 Streptococcus pyogenes Isolates in The Netherlands from 1959 to 1996
ABSTRACT Invasive group A streptococcal (GAS) disease reemerged in The Netherlands in the late 1980s. To seek an explanation for this resurgence, the genetic compositions of 22 M1 and 19 M28 GAS strains isolated in The Netherlands between 1960s and the mid-1990s were analyzed by using a mixed-genome DNA microarray. During this four-decade period, M1 and especially M28 strains acquired prophages on at least eight occasions. All prophages carried a superantigen (s peA2 , spe C, spe K) or a streptodornase ( sdaD2 , sdn ), both associated with invasive GAS disease. Invasive and noninvasive GAS str... Mehr ...
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Dokumenttyp: | Artikel |
Erscheinungsdatum: | 2007 |
Reihe/Periodikum: | Infection and Immunity ; volume 75, issue 7, page 3673-3679 ; ISSN 0019-9567 1098-5522 |
Verlag/Hrsg.: |
American Society for Microbiology
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Schlagwörter: | Infectious Diseases / Immunology / Microbiology / Parasitology |
Sprache: | Englisch |
Permalink: | https://search.fid-benelux.de/Record/base-26800229 |
Datenquelle: | BASE; Originalkatalog |
Powered By: | BASE |
Link(s) : | http://dx.doi.org/10.1128/iai.01695-06 |