Investigation of MALDI-TOF Mass Spectrometry for Assessing the Molecular Diversity of Campylobacter jejuni and Comparison with MLST and cgMLST: A Luxembourg One-Health Study
There is a need for active molecular surveillance of human and veterinary Campylobacter infections. However, sequencing of all isolates is associated with high costs and a considerable workload. Thus, there is a need for a straightforward complementary tool to prioritize isolates to sequence. In this study, we proposed to investigate the ability of MALDI-TOF MS to pre-screen C. jejuni genetic diversity in comparison to MLST and cgMLST. A panel of 126 isolates, with 10 clonal complexes (CC), 21 sequence types (ST) and 42 different complex types (CT) determined by the SeqSphere+ cgMLST, were ana... Mehr ...
Verfasser: | |
---|---|
Dokumenttyp: | doc-type:article |
Erscheinungsdatum: | 2021 |
Verlag/Hrsg.: |
Saarländische Universitäts- und Landesbibliothek
|
Schlagwörter: | ddc:610 / Campylobacter / MALDI-TOF MS / subtyping / MLST / cgMLST / machine learning |
Sprache: | Englisch |
Permalink: | https://search.fid-benelux.de/Record/base-26742519 |
Datenquelle: | BASE; Originalkatalog |
Powered By: | BASE |
Link(s) : | http://nbn-resolving.org/urn:nbn:de:bsz:291--ds-350436 |