Molecular biological illustration of the idea of evolutionary search with BioRS.
(A) General idea of the battery of (identical) modules as it is formulated by Babiskin & Smolke [ 82 ]. (B) Our scheme of sequential search from scratch of a tetrameric aptamer. (C) Search scheme for a classic RS function with 4 BBs (above). Domains (BBs) separated by insulating spacers of predetermined length are searched sequentially from left to right. Delta is an increment of fitness level for each correctly found aptamer (BB). See text and legend to Fig 2 for the detailed description of an aptamer structure.