Risk stratification for colorectal neoplasia detection in the Flemish colorectal cancer screening programme

Abstract: Background The quantitative faecal immunochemical test (FIT) detects pre-cancerous lesions and colorectal cancer (CRC). Current CRC screening programmes are based upon a binary FIT result. This study evaluates the possibility of personalised risk prediction, based on FIT, age and gender to gain more insight into improving discrimination between normal outcomes, pre-cancerous lesions, carcinoma in situ and CRC working towards a more tailored screening approach. Methods In this retrospective study, from October 2013 until July 2016, data from 57,421 participants who underwent a colonos... Mehr ...