Prevalence of at-risk genotypes for genotoxic effects decreases with age in a randomly selected population in Flanders: a cross sectional study
Abstract Background We hypothesized that in Flanders (Belgium), the prevalence of at-risk genotypes for genotoxic effects decreases with age due to morbidity and mortality resulting from chronic diseases. Rather than polymorphisms in single genes, the interaction of multiple genetic polymorphisms in low penetrance genes involved in genotoxic effects might be of relevance. Methods Genotyping was performed on 399 randomly selected adults (aged 50-65) and on 442 randomly selected adolescents. Based on their involvement in processes relevant to genotoxicity, 28 low penetrance polymorphisms affecti... Mehr ...
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Dokumenttyp: | Artikel |
Erscheinungsdatum: | 2011 |
Reihe/Periodikum: | Environmental Health ; volume 10, issue 1 ; ISSN 1476-069X |
Verlag/Hrsg.: |
Springer Science and Business Media LLC
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Schlagwörter: | Health / Toxicology and Mutagenesis / Public Health / Environmental and Occupational Health |
Sprache: | Englisch |
Permalink: | https://search.fid-benelux.de/Record/base-26696247 |
Datenquelle: | BASE; Originalkatalog |
Powered By: | BASE |
Link(s) : | http://dx.doi.org/10.1186/1476-069x-10-85 |