Introduction: The primary care system in Flanders (Belgium) was substantially reoriented and restructured. At local level Primary Care Zones (PCZs) were installed to support better coordination and connect care and welfare organizations with local authorities. The province of Limburg counts 8 active PCZs and is one of the five provinces of Flanders. The province boasts an interesting mining history, forests and historic towns. Collaboration and exchange between primary care actors and knowledge institutions (universities of applied sciences and universities) offers opportunities to translate and implement evidence-based concepts and innovations in the sector. Vice versa, the sector's practical knowledge feeds scientific research and education in the knowledge institutions. Description: Limburg has a well-established tradition of collaboration between the healthcare and welfare sector and the knowledge institutions (Hasselt University and University Colleges PXL and UCLL). The PCZs and knowledge institutions aim to further strengthen this existing collaboration and embed it in the Health Campus Limburg (as a tangible meeting ground for primary care in Limburg). This creates a unique partnership between practice (healthcare & welfare), knowledge (research and education) and campus development (innovation ecosystem). The initiative - called 'CELL' was launched on October 5th of 2022 in Hasselt. A charter was signed by 17 Limburg organizations. In addition to 6 PCZs, the 3 knowledge institutions and Health Campus Limburg, the 2 Limburg hospital networks (South-West and North-East Limburg), the 3 mental healthcare networks (Reling, Noolim, Ligant), the palliative care network (Pallion) and the Logo Limburg (prevention network) also joined. The 3 knowledge institutes will collaborate intensively within the CELL initiative in the coming years to strengthen primary care in Limburg. CELL aims to facilitate integrated care at a regional level through innovation processes and projects. Limburg can act as a testing ...